Patients on subcutaneous allergen immunotherapy are at risk of intramuscular injections

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Patients on subcutaneous allergen immunotherapy are at risk of intramuscular injections

BACKGROUND Allergen-specific subcutaneous immunotherapy is an effective treatment for certain allergic disorders. Ideally, it should be administered into the subcutaneous space in the mid-posterolateral upper arm. Injections are commonly given using a standard allergy syringe with a needle length of 13 mm. Therefore, there is a risk of intramuscular administration if patients have a skin-to-mus...

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To find out whether diabetic children may inject their insulin intramuscularly rather than subcutaneously, a random sample of 32 patients aged 4.3-17.9 (median 11.3) years was studied. Distance from skin to muscle fascia was measured by ultrasonography at standard injection sites on the outer arm, anterior and lateral thigh, abdomen, buttock, and calf. Distances were greater in girls (n = 15) t...

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Syringe contamination following intramuscular and subcutaneous injections.

FOR many years it had been customary to give a series of intravenous injections of a drug such as neoarsphenamine with the same syringe, merely rinsing the syringe with antiseptic and distilled water before passing on to the next patient. Largely as a result of investigation of cases of postarsphenamine jaundice it has become recognized in recent years that a syringe which has been used for an ...

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Immunotherapy – 2071. Strail levels decreased after allergen-subcutaneous specific immunotherapy

Background TRAIL is present in cells involved in asthma including eosinophils, mast cells, fibroblasts, and airway epithelial cells. It is expressed in airway remodeling and may be linked with the pathways of transforming growth factorbeta1, which is thought to cause damage to the epithelium. The repair process of the epithelium is hindered as a result of increased apoptosis induced by TGF-beta...

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Recent Progress in Allergen Immunotherapy

The efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. Immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

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ژورنال

عنوان ژورنال: Allergy, Asthma & Clinical Immunology

سال: 2014

ISSN: 1710-1492

DOI: 10.1186/1710-1492-10-22